Ukr. Bot. J. 2014, 71(5): 620–625 https://doi.org/10.15407/ukrbotj71.05.620Plant Physiology, Biochemistry, Cell and Molecular Biology
Cell cycle regulators in Arabidopsis thaliana transgenic plants under clinorotation. Cyclin-depending kinases
O. Artemenko- M. G. Kholodny Institute of Botany, National Academy of Sciences of Ukraine
Abstract
The main cell cycle regulators in plants, as in all eukaryotes, are cyclin and cyclin-depending kinases (CDK). They form active complex to initiate a cascade of reactions during cell cycle progression. In this article the generalized data about classification, properties of these proteins and their role in cell cycle regulation in the model plant Arabidopsis thaliana (L) Heynh. are presented. The following issues are emphasized: δ-cyclins genes (from D-class of cyclins), very important for cell progression across presyntetic phase of the cell cycle, which are responsible for cell transition from quiescence stage in DNA-synthesis phase (S) and can be regulated by exogenic factors; and CDK2, which combines this class of cyclins to form an active CDK-cyclin complex. Each cyclin is synthesized and degrades in the cell for specific period of the cycle and their expression fluctuates during a whole cell cycle [2], whereas CDKs is present in the cell all the time. Therefore, the study of CDK is necessary for understanding the fundamental cell cycle control mechanisms.
Keywords: cell cycle, cyclin-depending kinase, cell cycle regulation, cyclin, gene expression
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